"India’s $ 1 Revolutionary Cancer Anti -Photo and Medicine" has attracted widespread attention. Is it hopes or hype?
Recently, the news of "India has developed a revolutionary cancer anti -recurring medicine tablet" in India "was widely circulated among domestic cancer patients.
According to media reports, after more than ten years of extensive research and testing, the Tata Institute of Mumbai has developed a oxidant tablets containing resveratrol and copper (R+CU).The side effects of cancer treatment are reduced by about 50%, and 30%of the curative effect is displayed in preventing the recurrence of cancer.
It is reported that the side effects of the pills have been tested on mice and human body, but the prevention test is only performed on mice. "Human testing is expected to take no less than five years to complete." DrLucknow Investment. Badve said.The pills priced at only 100 rupees (about $ 1.2) are waiting for the approval of the Indian Food Safety and Standards Agency (FSSAL), which may be listed between June and July 2024.
Cancer is the enemy of humans. On February 2, 2024, the latest data released by the World Health Organization International Cancer Research Agency (IARC) showed that the number of new cancer cases worldwide in 2022 reached 20 million cases and 9.7 million deaths.The number of new cancer cases in the year will exceed 35 million, and the mortality may double.
In the past ten years, cancer treatment and disease management have made great progress in improving patients’ prognosis and quality of survival.However, cancer is still one of the most important deaths in the world.The increasing global cancer burden is worthy of great importance to the world.
For the "revolutionary" drug in India, Zhang Hongtao, an associate professor of research associate professor at the University of Pennsylvania and the current Hangzhou Saidang Biotechnology Co., Ltd., told the 21st Century Business Herald that "Resveid lotus is a health product, a natural plant, a natural plantThe components in Chinese or medicinal materials have no evidence and approval at present, it can be used as a drug to treat any disease, whether it is tumor or Alzheimer’s disease. "
Hope or hype?
According to reports, the oxidant pills of R+CU are expected to be effective in pancreatic cancer, lung cancer and oral cancer.
Dr. Badve explained to the Indian media, "Human cancer cells are implanted in mice for research and tumors are formed in miceVaranasi Investment. Then radiotherapy, chemotherapy and surgical treatment of mice. Studies have found that when these cancer cells die, they will be brokenCracks into small pieces called chromatin particles.
In response to this problem, the researchers took the oxidant pills containing R+CU for rats.The R+CU pill can produce oxygen free radicals and effectively destroy chromatin particles.During orally, these pills release oxygen free radicals in the stomach and quickly enter the blood.This process prevents cell chromatin particles from being released in the blood circulation and inhibit the movement of cancer cells. This process is called metastasis.Researchers also claim that the R+Cu tablets can reduce the toxicity brought by chemotherapy.Pune Investment
The 21st Century Economic Herald reporter found that shortly after the release of the above news in many Indian media, ICMR’s honorary scientists and Maderas Diabetes Research Foundation (MDRF), a Maderas Diabetes Research Foundation (MDRF), in India, DrNew Delhi Stock Exchange. MDRF published "R+CUCancer treatment prospects: Hope or hype? "The article pointed out that" the new, economic and affordable cancer treatment method developed by the Mumbai Tata Institute can prevent cancer from recurring, which can be called a major breakthrough in medicine.Hope and hype ""
According to him, this pill is aimed at the potential cause of cancer recurrence: the cell fragments released when cancer cells died -CFCHPS (CFCHPS), which can induce healthy cell cancer.R+Cu contains resveratrol and copper, which can generate oxygen free radicals in the stomach, enter the blood and destroy these CFCHPS.Kolkata Wealth Management
M Balasubramanyam emphasized that although the researchers called their discovery as "the magic of R+CU", there were also gimmicks, "the fundamental mechanism of cancer and its recurrence is more complicated.R+CU therapy is like a ‘double -edged sword’.
For the efficacy and security of R+CU in the human body, Dr. M Balasubramanyam lists key issues, including the extent of the results of rats in terms of cancer recurrence;Any test to evaluate the oxidation reduction balance and the burden of oxidant in the patient’s body; before using R+CU, you need to detect whether the patient lacks copper or copper toxicity;Reactor.
In this regard, Zhang Hongtao further stated to the 21st Century Business Herald that "Cell fragments released during the death of cancer cells are DNA, RNA, or others. It must be proved by experiments to prove that these ‘fragments’ can indeed cause normal cell cancer to turn cancer cancer."" "
In addition, the 21st Century Business Herald also noticed that as a key node from June to July 2024, different from the drug listing nodes displayed by the media, Dr. M Balasubramanyam said the node drug would enter the clinical trial of the human body.
Zhang Hongtao believes, "If it is a health product, there is no problem in listing and sales after the product is well, but it cannot be sold according to drugs. If you want to claim that it has anti -cancer function, it must be proved by clinical trials, especially to prevent cancer, clinical clinical clinical, clinical clinical.It may not be finished in 10 years and 8 years, but it also involves the supervision of relevant Indian departments. "
Does resveratrol have anti -cancer effects?
There are different views in the industry for the new R+CU drugs of the Mumbai Institute.
Some people in the industry told the 21st Century Business Herald that "The approval process of the listing of new Indian drugs is not very clear, but it is generally necessary to go on the market. Although resveratrol is a health product component, if a large dose is a large dose, it will not rule out that the large dose is not ruled out that it does not rule out that it does not rule out that it does not rule out the large dose.As the possibility of treatment of drugs, and the proportion or synthesis relationship between resveratrol and copper is still unclear, this requires more details. "
A "Research Progress of Clinical Application of Resveratrol" published in the Journal of Xinxiang Medical College shows that resveratrol is a natural polyphenol compound, which is mainly derived from peanuts, red grapes, slot waters, mulberry, etc.plant.Resveratrol can be used as preventive drugs for cardiovascular system diseases and neurodegenerative diseases. It has a positive treatment effect in terms of cardiovascular system diseases, autoimmune diseases, neurological diseases, and cancer.
Published in 2021 published in the article "Internet Warnal of Molecular Sciences" shows that resveratrol can regulate cancer -related molecular mechanisms, which indicates that it may be used as a adult application for cancer management.Although the hopeful effects of different types of cancer types are observed in in vitro research, the clinical transformation is still greatly limited due to the low biological utilization of resveratrol.
The 21st Century Economic Herald used "Resveratrol" as the keyword. The two small molecular chemicals were found in the smart buds of the new drug intelligence library, and the target was SIRT1.One of them was developed by the University of California Los Angeles and Naked Biome. The indication was ordinary acne and is currently in a clinical phase 1.Another is developed by Protheragen for the treatment of Alzheimer’s disease, which is currently clinically clinically.
Based on the above data, resveratrol has endorsed the clinical data of cancer’s related efficacy.However, with the aging population and the rapid growth of the population, the stack of relevant risk factors has continued to change, and cancer is still a mountain that is still in the process of human civilization, and many pharmaceutical companies and social forces are also striving for overcome.
The 21st Century Economic Herald noticed that cooperation and breakthroughs in the field of cancer treatment have continued.On March 13th, Pearl Bio announced that it signed a license, cooperation and selection agreement with Murishadon (MSD), and will use its proprietary Genomically Recoded Organisms to jointly discover and develop cancer, developing cancer, and developing cancer.Biological products containing non -standard amino acids.
In addition, a study published on the New England Medical Journal (NEJM) shows that three recurrent glue female cytoma (GBM) patients were treated after receiving CAR-T cell therapy named CARV3-Team-E, andThe brain tumor was rapidly narrowed in 1-5 days, and the tumor of one of the patients almost completely disappeared on the 5th day.
Asgard therapeutics announced the completion of 30 million euros transactions to support its main project AT-108 to reach the state of submitting IND applications by 2026.Based on a number of papers published on Science Immunology, AT-108 has achieved preclinical conceptual verification in the in vitro model derived from patients and internal models of rodents.This therapy has transformed nearly 100 different types of cancer cells into immune cells.Even as a single therapy, powerful anti -tumor immune response and remote effects are stimulated in animals.
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